Reactome | F-actin [cytosol]

Schema > Polymer > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-5218769] HSP27 oligomer:F-actin [cytosol] - Sus scrofa [Complex:R-SSC-5626510] RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] - Sus scrofa [Complex:R-SSC-430323] Migfilin:Filamin A:F-actin [cytosol] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-5626507] IQGAPs bind F-actin, which is inhibited by calmodulin - Sus scrofa [Reaction:R-SSC-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin - Sus scrofa [Reaction:R-SSC-430347] MigFilin associates with Filamin and F-actin - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10478379
displayName	F-actin [cytosol]
inDisease	false
inferredFrom	[Polymer:R-HSA-201877] F-actin [cytosol] - Homo sapiens
maxDepth	3
name	F-actin
producedByEvent	[BlackBoxEvent:R-SSC-5218916] p-MAPK2/3 phosphorylates HSP27 - Sus scrofa
repeatedUnit	[Complex:R-SSC-201857] G-actin [cytosol]
schemaClass	Polymer
species	[Species:49633] Sus scrofa
stId	R-SSC-201877
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-5626507] IQGAPs bind F-actin, which is inhibited by calmodulin [Reaction:R-SSC-430347] MigFilin associates with Filamin and F-actin [Reaction:R-SSC-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin
(hasComponent)	[Complex:R-SSC-5626510] RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] [Complex:R-SSC-5218769] HSP27 oligomer:F-actin [cytosol] [Complex:R-SSC-430323] Migfilin:Filamin A:F-actin [cytosol] [Complex:R-SSC-1861699] Mother filament:branching complex:daughter filament [cytosol] [Complex:R-SSC-2197686] Mother filament:ARP2/3:actin:ADP [cytosol] [Complex:R-SSC-2029140] Mother filament:branching complex [cytosol]
(output)	[BlackBoxEvent:R-SSC-5218916] p-MAPK2/3 phosphorylates HSP27
(inferredTo)	[Polymer:R-HSA-201877] F-actin [cytosol]

Cite Us!