Reactome | F-actin [cytosol]

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F-actin [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-443655] pL1:ERM:F-actin [plasma membrane] - Homo sapiens [Complex:R-HSA-443668] pL1:Shootin-1:F-actin [plasma membrane] - Homo sapiens [Complex:R-HSA-2197686] Mother filament:ARP2/3:actin:ADP [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-373736] Shootin-1 links L1 and retrograde actin flow - Homo sapiens [Reaction:R-HSA-443779] Linkage of L1 with treadmilling F-actin - Homo sapiens [Reaction:R-HSA-5626507] IQGAPs bind F-actin, which is inhibited by calmodulin - Homo sapiens [Reaction:R-HSA-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin - Homo sapiens [Reaction:R-HSA-433725] Interaction of Afadin with F-actin - Homo sapiens [Reaction:R-HSA-430347] MigFilin associates with Filamin and F-actin - Homo sapiens
created	[InstanceEdit:201880] Matthews, L, 2007-10-02 06:58:32
crossReference	[DatabaseIdentifier:9667283] ChEBI:36080
dbId	201877
displayName	F-actin [cytosol]
inDisease	false
inferredTo	[Polymer:R-MMU-201877] F-actin [cytosol] - Mus musculus [Polymer:R-RNO-201877] F-actin [cytosol] - Rattus norvegicus [Polymer:R-CFA-201877] F-actin [cytosol] - Canis familiaris [Polymer:R-BTA-201877] F-actin [cytosol] - Bos taurus [Polymer:R-SSC-201877] F-actin [cytosol] - Sus scrofa [Polymer:R-DRE-201877] F-actin [cytosol] - Danio rerio [Polymer:R-XTR-201877] F-actin [cytosol] - Xenopus tropicalis [Polymer:R-GGA-201877] F-actin [cytosol] - Gallus gallus [Polymer:R-DME-201877] F-actin [cytosol] - Drosophila melanogaster [Polymer:R-CEL-201877] F-actin [cytosol] - Caenorhabditis elegans [Polymer:R-DDI-201877] F-actin [cytosol] - Dictyostelium discoideum [Polymer:R-SPO-201877] F-actin [cytosol] - Schizosaccharomyces pombe [Polymer:R-SCE-201877] F-actin [cytosol] - Saccharomyces cerevisiae
modified	[InstanceEdit:9667994] D'Eustachio, Peter, 2019-11-18
name	F-actin
producedByEvent	[BlackBoxEvent:R-HSA-5218916] p-MAPK2/3 phosphorylates HSP27 - Homo sapiens [Reaction:R-HSA-445089] Dephosphorylation of pL1 (Y1176) - Homo sapiens
repeatedUnit	[Complex:R-HSA-201857] G-actin [cytosol]
schemaClass	Polymer
species	[Species:48887] Homo sapiens
stId	R-HSA-201877

Referrals

(hasComponent)	[Complex:R-HSA-443668] pL1:Shootin-1:F-actin [plasma membrane] [Complex:R-HSA-443655] pL1:ERM:F-actin [plasma membrane] [Complex:R-HSA-392744] SPTA:SPTB:F-actin [cytosol] [Complex:R-HSA-5218769] HSP27 oligomer:F-actin [cytosol] [Complex:R-HSA-5626510] RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] [Complex:R-HSA-2197686] Mother filament:ARP2/3:actin:ADP [cytosol] [Complex:R-HSA-1861699] Mother filament:branching complex:daughter filament [cytosol] [Complex:R-HSA-2029140] Mother filament:branching complex [cytosol] [Complex:R-HSA-430323] Migfilin:Filamin A:F-actin [cytosol] [Complex:R-HSA-433726] Afadin:F-actin [cytosol]
(input)	[Reaction:R-HSA-373736] Shootin-1 links L1 and retrograde actin flow [Reaction:R-HSA-443779] Linkage of L1 with treadmilling F-actin [Reaction:R-HSA-5626507] IQGAPs bind F-actin, which is inhibited by calmodulin [Reaction:R-HSA-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin [Reaction:R-HSA-430347] MigFilin associates with Filamin and F-actin [Reaction:R-HSA-433725] Interaction of Afadin with F-actin
(output)	[Reaction:R-HSA-445089] Dephosphorylation of pL1 (Y1176) [BlackBoxEvent:R-HSA-5218916] p-MAPK2/3 phosphorylates HSP27

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