Reactome | Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-213135] Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-198315] Active IRS recruits PI3K to the plasma membrane and activates it - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10464702
displayName	Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane]
hasComponent	[Complex:R-SSC-187031] mature beta-NGF homodimer [extracellular region] [DefinedSet:R-SSC-112322] p-Y-IRS1,p-Y-IRS2 [cytosol] 2 × [EntityWithAccessionedSequence:R-SSC-3009413] phospho-p-5Y-NTRK1 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Homo sapiens
maxDepth	3
name	Activated TrkA receptor:Phospho-IRS1/2
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-198299
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-198315] Active IRS recruits PI3K to the plasma membrane and activates it
(hasComponent)	[Complex:R-SSC-213135] Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane]
(inferredTo)	[Complex:R-HSA-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane]

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