Reactome | Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10464705] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10464704
displayName	Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane]
hasComponent	[Complex:R-SSC-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] [Complex:R-SSC-74693] PI3K [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-213135] Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] - Homo sapiens
maxDepth	4
name	Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110)
producedByEvent	[Reaction:R-SSC-198315] Active IRS recruits PI3K to the plasma membrane and activates it - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-213135
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10464705] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane]
(output)	[Reaction:R-SSC-198315] Active IRS recruits PI3K to the plasma membrane and activates it
(inferredTo)	[Complex:R-HSA-213135] Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane]

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