Reactome | Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane]

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Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-213135] Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-198315] Active IRS recruits PI3K to the plasma membrane and activates it - Homo sapiens
created	[InstanceEdit:198310] 2007-07-10 08:01:55
dbId	198299
displayName	Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane]
hasComponent	[Complex:R-HSA-167057] beta-NGF homodimer [extracellular region] 2 × [EntityWithAccessionedSequence:R-HSA-3009413] p-5Y-NTRK1 [plasma membrane] [DefinedSet:R-HSA-112322] p-Y-IRS1,p-Y-IRS2 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Mus musculus [Complex:R-RNO-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Canis familiaris [Complex:R-BTA-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Bos taurus [Complex:R-SSC-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Sus scrofa [Complex:R-DRE-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Danio rerio [Complex:R-XTR-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - Gallus gallus
maxDepth	3
modified	[InstanceEdit:9634148] Jassal, Bijay, 2019-01-07
name	Activated TrkA receptor:Phospho-IRS1/2
producedByEvent	[Reaction:R-HSA-198295] TRKA phosphorylates IRS - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-198299
updateTrackers	[UpdateTracker:9875209] Update Tracker - [Complex:198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - v44:[add_removeHasComponent, updateContainedComponent] [UpdateTracker:9900220] Update Tracker - [Complex:198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - v68:[add_removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9875209] Update Tracker - [Complex:198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - v44:[add_removeHasComponent, updateContainedComponent] [UpdateTracker:9900220] Update Tracker - [Complex:198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - v68:[add_removeHasComponent]
(output)	[Reaction:R-HSA-198295] TRKA phosphorylates IRS
(hasComponent)	[Complex:R-HSA-213135] Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane]
(input)	[Reaction:R-HSA-198315] Active IRS recruits PI3K to the plasma membrane and activates it

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