Reactome | Translocation of Cdc25 to the nucleus

Schema > Reaction > Entries

Translocation of Cdc25 to the nucleus Show undefined attributes

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10459852
displayName	Translocation of Cdc25 to the nucleus
eventOf	[Pathway:R-SSC-69273] Cyclin A/B1/B2 associated events during G2/M transition - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-170153] Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases - Sus scrofa [Reaction:R-SSC-170120] Translocation of Cdc25B to the cytoplasm - Sus scrofa [Reaction:R-SSC-9929935] CCNA:CDK1 phosphorylates CDC25B - Sus scrofa [Reaction:R-SSC-170158] CDC25A dephosphorylates CCNA:CDK1 - Sus scrofa
inferredFrom	[Reaction:R-HSA-170159] Translocation of Cdc25 to the nucleus - Homo sapiens
input	[DefinedSet:R-SSC-170108] CDC25 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of Cdc25 to the nucleus
output	[DefinedSet:R-SSC-69261] CDC25 [nucleoplasm]
precedingEvent	[Reaction:R-SSC-156678] Activation of Cdc25C - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-170159
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-69273] Cyclin A/B1/B2 associated events during G2/M transition
(precedingEvent)	[Reaction:R-SSC-9929935] CCNA:CDK1 phosphorylates CDC25B [Reaction:R-SSC-170153] Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases [Reaction:R-SSC-170158] CDC25A dephosphorylates CCNA:CDK1 [Reaction:R-SSC-170120] Translocation of Cdc25B to the cytoplasm
(inferredTo)	[Reaction:R-HSA-170159] Translocation of Cdc25 to the nucleus