Reactome | Translocation of Cdc25 to the nucleus

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Translocation of Cdc25 to the nucleus Show undefined attributes

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:170148] Matthews, L, 2005-12-23 13:53:48
dbId	170159
displayName	Translocation of Cdc25 to the nucleus
eventOf	[Pathway:R-HSA-69273] Cyclin A/B1/B2 associated events during G2/M transition - Homo sapiens
followingEvent	[Reaction:R-HSA-170153] Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases - Homo sapiens [Reaction:R-HSA-170120] Translocation of Cdc25B to the cytoplasm - Homo sapiens [Reaction:R-HSA-9929935] CCNA:CDK1 phosphorylates CDC25B - Homo sapiens [Reaction:R-HSA-170158] CDC25A dephosphorylates CCNA:CDK1 - Homo sapiens
input	[DefinedSet:R-HSA-170108] CDC25 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:170222] Cdc25A localisation and shuttling: characterisation of sequences mediating nuclear export and import [LiteratureReference:170197] Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress [LiteratureReference:75017] Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Translocation of Cdc25 to the nucleus
negativePrecedingEvent	[NegativePrecedingEvent:9764051] Futile Cycle: Translocation of Cdc25B to the cytoplasm
orthologousEvent	[Reaction:R-MMU-170159] Translocation of Cdc25 to the nucleus - Mus musculus [Reaction:R-SCE-170159] Translocation of Cdc25 to the nucleus - Saccharomyces cerevisiae [Reaction:R-SPO-170159] Translocation of Cdc25 to the nucleus - Schizosaccharomyces pombe [Reaction:R-DDI-170159] Translocation of Cdc25 to the nucleus - Dictyostelium discoideum [Reaction:R-CEL-170159] Translocation of Cdc25 to the nucleus - Caenorhabditis elegans [Reaction:R-DME-170159] Translocation of Cdc25 to the nucleus - Drosophila melanogaster [Reaction:R-GGA-170159] Translocation of Cdc25 to the nucleus - Gallus gallus [Reaction:R-XTR-170159] Translocation of Cdc25 to the nucleus - Xenopus tropicalis [Reaction:R-DRE-170159] Translocation of Cdc25 to the nucleus - Danio rerio [Reaction:R-SSC-170159] Translocation of Cdc25 to the nucleus - Sus scrofa [Reaction:R-BTA-170159] Translocation of Cdc25 to the nucleus - Bos taurus [Reaction:R-CFA-170159] Translocation of Cdc25 to the nucleus - Canis familiaris [Reaction:R-RNO-170159] Translocation of Cdc25 to the nucleus - Rattus norvegicus
output	[DefinedSet:R-HSA-69261] CDC25 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-156678] Activation of Cdc25C - Homo sapiens
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-170159
summation	[Summation:170202] The localization of the Cdc25A, B and C proteins is dynamic ...
updateTrackers	[UpdateTracker:9781270] Update Tracker - [Reaction:170159] Translocation of Cdc25 to the nucleus - v61:[add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9781270] Update Tracker - [Reaction:170159] Translocation of Cdc25 to the nucleus - v61:[add_removeOutput]
(hasEvent)	[Pathway:R-HSA-69273] Cyclin A/B1/B2 associated events during G2/M transition
(precedingEvent)	[Reaction:R-HSA-9929935] CCNA:CDK1 phosphorylates CDC25B [Reaction:R-HSA-170153] Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases [Reaction:R-HSA-170158] CDC25A dephosphorylates CCNA:CDK1 [Reaction:R-HSA-170120] Translocation of Cdc25B to the cytoplasm

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