Reactome | Processing and activation of SUMO

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Processing and activation of SUMO Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11079405
displayName	Processing and activation of SUMO
eventOf	[Pathway:R-SPO-2990846] SUMOylation - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:4162] protein sumoylation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-SPO-3065679] SUMO is proteolytically processed - Schizosaccharomyces pombe [Pathway:R-SPO-3065676] SUMO is conjugated to E1 (UBA2:SAE1) - Schizosaccharomyces pombe [Pathway:R-SPO-3065678] SUMO is transferred from E1 to E2 (UBE2I, UBC9) - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-3215018] Processing and activation of SUMO - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Processing and activation of SUMO
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-3215018
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-2990846] SUMOylation
(inferredTo)	[Pathway:R-HSA-3215018] Processing and activation of SUMO

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