Reactome | SUMO is conjugated to E1 (UBA2:SAE1)

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11079403
displayName	SUMO is conjugated to E1 (UBA2:SAE1)
eventOf	[Pathway:R-SPO-3215018] Processing and activation of SUMO - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SPO-2990833] Conjugation of SUMO1 to UBA2:SAE1 - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-3065676] SUMO is conjugated to E1 (UBA2:SAE1) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SUMO is conjugated to E1 (UBA2:SAE1)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-3065676
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-3215018] Processing and activation of SUMO
(inferredTo)	[Pathway:R-HSA-3065676] SUMO is conjugated to E1 (UBA2:SAE1)

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