Reactome | Phase I - Functionalization of compounds

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Phase I - Functionalization of compounds Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:70616] mitochondrial inner membrane [Compartment:17906] mitochondrial outer membrane [Compartment:5460] mitochondrial matrix [Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11078389
displayName	Phase I - Functionalization of compounds
eventOf	[Pathway:R-SPO-211859] Biological oxidations - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-SPO-211897] Cytochrome P450 - arranged by substrate type - Schizosaccharomyces pombe [Pathway:R-SPO-71384] Ethanol oxidation - Schizosaccharomyces pombe [Reaction:R-SPO-5689000] AADAC deacetylates PHEN - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-211945] Phase I - Functionalization of compounds - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Phase I - Functionalization of compounds
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-211945
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-211859] Biological oxidations
(inferredTo)	[Pathway:R-HSA-211945] Phase I - Functionalization of compounds

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