Reactome | Ethanol oxidation

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Ethanol oxidation Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11078387
displayName	Ethanol oxidation
eventOf	[Pathway:R-SPO-211945] Phase I - Functionalization of compounds - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:14935] ethanol catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SPO-71707] ethanol + NAD+ => acetaldehyde + NADH + H+ - Schizosaccharomyces pombe [Reaction:R-SPO-71723] acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] - Schizosaccharomyces pombe [Reaction:R-SPO-5696091] ALDH1B1 tetramer oxidises CH3CHO to CH3COOH - Schizosaccharomyces pombe [Reaction:R-SPO-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Schizosaccharomyces pombe [Reaction:R-SPO-71691] acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] - Schizosaccharomyces pombe [Reaction:R-SPO-71735] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] - Schizosaccharomyces pombe [Reaction:R-SPO-5692237] ADH5 oxidises S-HMGSH to S-FGSH - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-71384] Ethanol oxidation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Ethanol oxidation Alcohol catabolism
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-71384
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-211945] Phase I - Functionalization of compounds
(inferredTo)	[Pathway:R-HSA-71384] Ethanol oxidation