Reactome | 1-acyl LPA is acylated to PA by AGPAT5 (OM)

Schema > Reaction > Entries

1-acyl LPA is acylated to PA by AGPAT5 (OM) Show undefined attributes

catalystActivity	[CatalystActivity:11062549] 1-acylglycerol-3-phosphate O-acyltransferase activity of AGPAT5 [mitochondrial outer membrane]
category	transition
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11062551
displayName	1-acyl LPA is acylated to PA by AGPAT5 (OM)
eventOf	[Pathway:R-SPO-1483166] Synthesis of PA - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-6801250] TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane - Schizosaccharomyces pombe [Reaction:R-SPO-1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Homo sapiens
input	[SimpleEntity:R-ALL-1500580] 1-acyl LPA [mitochondrial outer membrane] [SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	1-acyl LPA is acylated to PA by AGPAT5 (OM)
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1500590] PA [mitochondrial outer membrane]
precedingEvent	[Reaction:R-SPO-1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) - Schizosaccharomyces pombe
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-1482548
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-1483166] Synthesis of PA
(precedingEvent)	[Reaction:R-SPO-6801250] TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane [Reaction:R-SPO-1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)
(inferredTo)	[Reaction:R-HSA-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM)