Reactome | 1-acyl LPA is acylated to PA by AGPAT5 (OM)

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1-acyl LPA is acylated to PA by AGPAT5 (OM) Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1500599] 1-acylglycerol-3-phosphate O-acyltransferase activity of AGPAT5 [mitochondrial outer membrane]
category	transition
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482525] Williams, MG, 2011-08-12
dbId	1482548
displayName	1-acyl LPA is acylated to PA by AGPAT5 (OM)
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483166] Synthesis of PA - Homo sapiens
followingEvent	[Reaction:R-HSA-6801250] TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane - Homo sapiens [Reaction:R-HSA-1483099] PA translocates from the outer to the inner mitochondrial membrane - Homo sapiens [Reaction:R-HSA-1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) - Homo sapiens
input	[SimpleEntity:R-ALL-1500580] 1-acyl LPA [mitochondrial outer membrane] [SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1482520] Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria
modified	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
name	1-acyl LPA is acylated to PA by AGPAT5 (OM)
orthologousEvent	[Reaction:R-DDI-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Dictyostelium discoideum [Reaction:R-CEL-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Caenorhabditis elegans [Reaction:R-GGA-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Gallus gallus [Reaction:R-SSC-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Sus scrofa [Reaction:R-BTA-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Bos taurus [Reaction:R-CFA-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Canis familiaris [Reaction:R-RNO-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Rattus norvegicus [Reaction:R-MMU-1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) - Mus musculus
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1500590] PA [mitochondrial outer membrane]
precedingEvent	[Reaction:R-HSA-1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) - Homo sapiens [Reaction:R-HSA-1482695] G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1482548
summation	[Summation:1482651] At the outer mitochondrial (OM) membrane, 1-acyl lysophospha...

Referrals

(hasEvent)	[Pathway:R-HSA-1483166] Synthesis of PA
(precedingEvent)	[Reaction:R-HSA-6801250] TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane [Reaction:R-HSA-1483099] PA translocates from the outer to the inner mitochondrial membrane [Reaction:R-HSA-1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM)