Reactome | FXN:ISD11:NFS1:ISCU [mitochondrial matrix]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:11062428] ferrous iron binding activity of FXN:ISD11:NFS1:ISCU [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-SPO-1362416] Frataxin binds iron - Schizosaccharomyces pombe
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11062427
displayName	FXN:ISD11:NFS1:ISCU [mitochondrial matrix]
hasComponent	2 × [EntityWithAccessionedSequence:R-SPO-1362390] FXN(81-210) [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-SPO-1362392] isd11 [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-SPO-1362391] isu1 [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-SPO-1362396] PXLP-K258-NFS1-1 [mitochondrial matrix]
inDisease	false
inferredFrom	[Complex:R-HSA-1362404] FXN:ISD11:NFS1:ISCU [mitochondrial matrix] - Homo sapiens
maxDepth	2
name	FXN:ISD11:NFS1:ISCU
producedByEvent	[Reaction:R-SPO-9866272] 2Fe-2S is inserted in UQCRFS1 - Schizosaccharomyces pombe
schemaClass	Complex
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-1362404
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-SPO-9866272] 2Fe-2S is inserted in UQCRFS1
(input)	[Reaction:R-SPO-1362416] Frataxin binds iron
(physicalEntity)	[CatalystActivity:11062428] ferrous iron binding activity of FXN:ISD11:NFS1:ISCU [mitochondrial matrix]
(inferredTo)	[Complex:R-HSA-1362404] FXN:ISD11:NFS1:ISCU [mitochondrial matrix]

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