Reactome | FXN(81-210) [mitochondrial matrix]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:5460] mitochondrial matrix
componentOf	[Complex:R-SPO-1362402] 2 Iron:FXN [mitochondrial matrix] - Schizosaccharomyces pombe [Complex:R-SPO-1362404] FXN:ISD11:NFS1:ISCU [mitochondrial matrix] - Schizosaccharomyces pombe [Complex:R-SPO-1362404] FXN:ISD11:NFS1:ISCU [mitochondrial matrix] - Schizosaccharomyces pombe [Complex:R-SPO-1362398] FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix] - Schizosaccharomyces pombe [Complex:R-SPO-1362398] FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix] - Schizosaccharomyces pombe
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11062418
displayName	FXN(81-210) [mitochondrial matrix]
endCoordinate	210
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-1362390] FXN(81-210) [mitochondrial matrix] - Homo sapiens
maxDepth	1
name	FXN(81-210) O74831
producedByEvent	[Reaction:R-SPO-9854405] Frataxin transfers Fe2+ to ACO2 - Schizosaccharomyces pombe
referenceEntity	[ReferenceGeneProduct:uniprot:O74831] UniProt:O74831
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-1362390
startCoordinate	81

(activeUnit)	[CatalystActivity:11077498] iron chaperone activity of FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix] [CatalystActivity:11062428] ferrous iron binding activity of FXN:ISD11:NFS1:ISCU [mitochondrial matrix]
(output)	[Reaction:R-SPO-9854405] Frataxin transfers Fe2+ to ACO2
(hasComponent)	[Complex:R-SPO-1362404] FXN:ISD11:NFS1:ISCU [mitochondrial matrix] [Complex:R-SPO-1362398] FXN:NFS1:ISD11:ISCU:2Fe-2S Cluster [mitochondrial matrix] [Complex:R-SPO-1362402] 2 Iron:FXN [mitochondrial matrix]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-1362390] FXN(81-210) [mitochondrial matrix]

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