Reactome | PXLP-K56-SRR dimer deaminates D-Ser

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PXLP-K56-SRR dimer deaminates D-Ser Show undefined attributes

catalystActivity	[CatalystActivity:11103911] D-serine ammonia-lyase activity of PXLP-K56-SRR dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11103913
displayName	PXLP-K56-SRR dimer deaminates D-Ser
eventOf	[Pathway:R-SCE-977347] Serine metabolism - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9014741] PXLP-K56-SRR dimer deaminates D-Ser - Homo sapiens
input	[SimpleEntity:R-ALL-376186] D-Ser [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PXLP-K56-SRR dimer deaminates D-Ser D-serine => NH4(+) + pyruvate
output	[SimpleEntity:R-ALL-31633] NH4+ [cytosol] [SimpleEntity:R-ALL-29398] PYR [cytosol]
precedingEvent	[Reaction:R-SCE-9014766] PXLP-K56-SRR dimer isomerises L-Ser to D-Ser - Saccharomyces cerevisiae
regulatedBy	[PositiveRegulation:R-HSA-111757] Positive regulation by 'ATP [cytosol]' [Requirement:R-GGA-352997] Requirement by 'Mg2+ [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-9014741
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-977347] Serine metabolism
(inferredTo)	[Reaction:R-HSA-9014741] PXLP-K56-SRR dimer deaminates D-Ser

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