Reactome | RAC1 GTPase cycle

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RAC1 GTPase cycle Show undefined attributes

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11108118
displayName	RAC1 GTPase cycle
eventOf	[Pathway:R-SCE-9012999] RHO GTPase cycle - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-9013143] RAC1 GEFs activate RAC1 - Saccharomyces cerevisiae [Reaction:R-SCE-9013144] RAC1 GAPs stimulate RAC1 GTPase activity - Saccharomyces cerevisiae [Reaction:R-SCE-9013147] RAC1 GDIs block activation of RAC1 - Saccharomyces cerevisiae [BlackBoxEvent:R-SCE-9691168] RAC1 translocates to the endoplasmic reticulum membrane - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-9013149] RAC1 GTPase cycle - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RAC1 GTPase cycle
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-9013149
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-9012999] RHO GTPase cycle
(inferredTo)	[Pathway:R-HSA-9013149] RAC1 GTPase cycle

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