Reactome | RAC1 GDIs block activation of RAC1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11103847
displayName	RAC1 GDIs block activation of RAC1
eventOf	[Pathway:R-SCE-9013149] RAC1 GTPase cycle - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9013147] RAC1 GDIs block activation of RAC1 - Homo sapiens
input	[Complex:R-SCE-5674631] RAC1:GDP [plasma membrane] [EntityWithAccessionedSequence:R-SCE-194478] RDI1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RAC1 GDIs block activation of RAC1
output	[Complex:R-SCE-9013179] RAC1:GDP:RAC1 GDIs [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-9013147
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-9013149] RAC1 GTPase cycle
(inferredTo)	[Reaction:R-HSA-9013147] RAC1 GDIs block activation of RAC1

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