Reactome | 4Fe-4S cluster assembles on CFD1:NBP35 scaffold

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4Fe-4S cluster assembles on CFD1:NBP35 scaffold Show undefined attributes

authored	[InstanceEdit:2564829] Lill, Roland, 2012-11-07
catalystActivity	[CatalystActivity:2564827] electron transfer activity of TAH18:DRE2 reduced [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2564823] May, B, 2012-11-07
dbId	2564822
displayName	4Fe-4S cluster assembles on CFD1:NBP35 scaffold
edited	[InstanceEdit:2564820] May, B, 2012-11-07
followingEvent	[BlackBoxEvent:R-SCE-2564817] CIA Targeting Complex transfers 4Fe-4S clusters to apoproteins - Saccharomyces cerevisiae
input	2 × [EntityWithAccessionedSequence:R-SCE-2564764] CFD1 [cytosol] 4 × [SimpleEntity:R-ALL-71160] Fe [cytosol] 2 × [Complex:R-SCE-2564810] NBP35:4Fe-4S [cytosol] 4 × [SimpleEntity:R-ALL-2566513] S [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2564713] A bridging [4Fe-4S] cluster and nucleotide binding are essential for function of the Cfd1-Nbp35 complex as a scaffold in iron-sulfur protein maturation [LiteratureReference:2564726] Crucial role of conserved cysteine residues in the assembly of two iron-sulfur clusters on the CIA protein Nar1 [LiteratureReference:2564732] The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol [LiteratureReference:2564717] A novel eukaryotic factor for cytosolic Fe-S cluster assembly [LiteratureReference:2564746] The eukaryotic P loop NTPase Nbp35: an essential component of the cytosolic and nuclear iron-sulfur protein assembly machinery
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	4Fe-4S cluster assembles on CFD1:NBP35 scaffold
orthologousEvent	[BlackBoxEvent:R-HSA-2564826] 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold - Homo sapiens
output	[Complex:R-SCE-2564803] CFD1:4Fe-4S:NBP35 [cytosol]
precedingEvent	[Reaction:R-SCE-2564819] NADPH reduces TAH18:DRE2 - Saccharomyces cerevisiae
regulatedBy	[Requirement:R-SCE-8952951] Requirement by 'ATM1 dimer [mitochondrial inner membrane]'
regulationReference	[RegulationReference:9642102] Requirement by 'ATM1 dimer [mitochondrial inner membrane]' Glutathione-coordinated [2Fe-2S] cluster: a viable physiological substrate for mitochondrial ABCB7 transport
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3018411] Uringa, Evert-Jan, 2013-02-05
schemaClass	BlackBoxEvent
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-2564822
summation	[Summation:2564707] A [4Fe-4S] cluster is assembled on a scaffold composed of th...
updateTrackers	[UpdateTracker:9781542] Update Tracker - [BlackBoxEvent:2564822] 4Fe-4S cluster assembles on CFD1:NBP35 scaffold - v60:[addRegulator, removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9781542] Update Tracker - [BlackBoxEvent:2564822] 4Fe-4S cluster assembles on CFD1:NBP35 scaffold - v60:[addRegulator, removeCatalystActivity]
(precedingEvent)	[BlackBoxEvent:R-SCE-2564817] CIA Targeting Complex transfers 4Fe-4S clusters to apoproteins