Reactome | Methylation

Schema > Pathway > Entries

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107162
displayName	Methylation
eventOf	[Pathway:R-SCE-156580] Phase II - Conjugation of compounds - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:258832] methylation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-174391] MAT1A multimers transfer Ado from ATP to L-Met - Saccharomyces cerevisiae [Reaction:R-SCE-174401] AHCY:NAD+ tetramer hydrolyses AdoHcy - Saccharomyces cerevisiae [Reaction:R-SCE-6800149] N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-156581] Methylation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Methylation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-156581
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-156580] Phase II - Conjugation of compounds
(inferredTo)	[Pathway:R-HSA-156581] Methylation