Reactome | Reactive oxygen species oxidize DNAJA1

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Reactive oxygen species oxidize DNAJA1 Show undefined attributes

category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10218789
displayName	Reactive oxygen species oxidize DNAJA1
eventOf	[Pathway:R-RNO-9841251] Mitochondrial unfolded protein response (UPRmt) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-9857076] Oxidized DNAJA1 binds HSPA1A,B (HSP70) displacing HSF1 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-9857090] Reactive oxygen species oxidize DNAJA1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-3371544] DNAJA1 [cytosol] [SimpleEntity:R-ALL-1250243] ROS [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Reactive oxygen species oxidize DNAJA1
output	[EntityWithAccessionedSequence:R-RNO-9857072] SOH-C149,C150-DNAJA1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9857090
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9841251] Mitochondrial unfolded protein response (UPRmt)
(precedingEvent)	[Reaction:R-RNO-9857076] Oxidized DNAJA1 binds HSPA1A,B (HSP70) displacing HSF1
(inferredTo)	[Reaction:R-HSA-9857090] Reactive oxygen species oxidize DNAJA1

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