Reactome | TGFBR3 regulates TGF-beta signaling

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TGFBR3 regulates TGF-beta signaling Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10225435
displayName	TGFBR3 regulates TGF-beta signaling
eventOf	[Pathway:R-RNO-9839373] Signaling by TGFBR3 - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-9839377] TGFB1,TGFB2 bind TGFBR3 - Rattus norvegicus [Reaction:R-RNO-9839390] TGFBR3 complex binds to TGFBR2 - Rattus norvegicus [Reaction:R-RNO-9839363] TGFBR3 phosphorylation by TGFBR2 complex - Rattus norvegicus [Reaction:R-RNO-9839378] TGFBR3 binding to ARRB1/2 - Rattus norvegicus [BlackBoxEvent:R-RNO-9839358] Endocytosis of TGFBR3:ARRB complex - Rattus norvegicus [Reaction:R-RNO-9839402] TGFBR3 binding to GIPC1 - Rattus norvegicus [BlackBoxEvent:R-RNO-9839401] TGFBR3 degradation - Rattus norvegicus [Reaction:R-RNO-9839368] TGFBR3(1-783) binds to TGFB1,TGFB2 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-9839389] TGFBR3 regulates TGF-beta signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	TGFBR3 regulates TGF-beta signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9839389
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9839373] Signaling by TGFBR3
(inferredTo)	[Pathway:R-HSA-9839389] TGFBR3 regulates TGF-beta signaling

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