Reactome | TGFBR3 degradation

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10217587
displayName	TGFBR3 degradation
eventOf	[Pathway:R-RNO-9839389] TGFBR3 regulates TGF-beta signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9839401] TGFBR3 degradation - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-9839336] Tgfbr3 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	TGFBR3 degradation
precedingEvent	[BlackBoxEvent:R-RNO-9839388] TGFBR3 translocation to plasma membrane - Rattus norvegicus
regulatedBy	[NegativeRegulation:10217588] Negative regulation by 'TGFB1,TGFB2:TGFBR3:GIPC1 [cytoplasmic side of plasma membrane]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9839401
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-9839389] TGFBR3 regulates TGF-beta signaling
(inferredTo)	[BlackBoxEvent:R-HSA-9839401] TGFBR3 degradation