Reactome | K7 ub-SQSTM1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10215173
displayName	K7 ub-SQSTM1 [cytosol]
endCoordinate	440
hasModifiedResidue	[GroupModifiedResidue:10215171] ubiquitinylated lysine (K63_polyubiquitin chain [cytosol]) at 7 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-9759088] K7 ub-SQSTM1 [cytosol] - Homo sapiens
maxDepth	1
name	K7 ub-SQSTM1 O08623
negativelyRegulates	[NegativeRegulation:10215181] Negative regulation by 'K7 ub-SQSTM1 [cytosol]'
producedByEvent	[Reaction:R-RNO-9759154] TRIM21 ubiquitinates SQSTM1 - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:O08623] UniProt:O08623
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9759088
startCoordinate	1

(output)	[Reaction:R-RNO-9759154] TRIM21 ubiquitinates SQSTM1
(regulator)	[NegativeRegulation:10215181] Negative regulation by 'K7 ub-SQSTM1 [cytosol]'
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-9759088] K7 ub-SQSTM1 [cytosol]

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