Reactome | MUL1 ubiquitinates UBXN7

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MUL1 ubiquitinates UBXN7 Show undefined attributes

catalystActivity	[CatalystActivity:10215039] ubiquitin protein ligase activity of MUL1 dimer [mitochondrial outer membrane]
category	transition
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10215041
displayName	MUL1 ubiquitinates UBXN7
eventOf	[Pathway:R-RNO-9755511] KEAP1-NFE2L2 pathway - Rattus norvegicus [Pathway:R-RNO-8951664] Neddylation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-RNO-9755306] ub UBXN7 is degraded by the 26S proteasome - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-9755304] MUL1 ubiquitinates UBXN7 - Homo sapiens
input	3 × [DefinedSet:R-RNO-113595] Ub [cytosol] [EntityWithAccessionedSequence:R-RNO-8956071] Ubxn7 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MUL1 ubiquitinates UBXN7
output	[EntityWithAccessionedSequence:R-RNO-9755305] Ubxn7 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9755304
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-8951664] Neddylation [Pathway:R-RNO-9755511] KEAP1-NFE2L2 pathway
(precedingEvent)	[BlackBoxEvent:R-RNO-9755306] ub UBXN7 is degraded by the 26S proteasome
(inferredTo)	[Reaction:R-HSA-9755304] MUL1 ubiquitinates UBXN7