Reactome | NLRX1 binds CHUK:IKBKB:IKBKG

Schema > Reaction > Entries

NLRX1 binds CHUK:IKBKB:IKBKG Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10214865
displayName	NLRX1 binds CHUK:IKBKB:IKBKG
eventOf	[Pathway:R-RNO-9758274] Regulation of NF-kappa B signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:162165] negative regulation of canonical NF-kappaB signal transduction
inferredFrom	[Reaction:R-HSA-9749471] NLRX1 binds CHUK:IKBKB:IKBKG - Homo sapiens
input	[Complex:R-RNO-168113] CHUK:IKBKB:IKBKG [cytosol] [EntityWithAccessionedSequence:R-RNO-9749510] K63polyUb-NLRX1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NLRX1 binds CHUK:IKBKB:IKBKG NLRX1 binds activated IKK complex
output	[Complex:R-RNO-9749472] CHUK:IKBKB:IKBKG:K63polyUb-NLRX1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9749471
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9758274] Regulation of NF-kappa B signaling
(inferredTo)	[Reaction:R-HSA-9749471] NLRX1 binds CHUK:IKBKB:IKBKG

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