Reactome | Hspa8 dissociates from Lamp2

Schema > Reaction > Entries

authored	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:17938] lysosomal membrane
created	[InstanceEdit:9626243] Varusai, Thawfeek, 2018-10-26
dbId	9626236
displayName	Hspa8 dissociates from Lamp2
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
followingEvent	[Reaction:R-RNO-9626275] Hsp90 dissociates from Lamp2 - Rattus norvegicus
input	[Complex:R-RNO-9626249] Hspa8:Lamp2 multimer [lysosomal membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9622837] The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hspa8 dissociates from Lamp2
orthologousEvent	[Reaction:R-HSA-9626235] HSPA8 dissociates from LAMP2a - Homo sapiens
output	[EntityWithAccessionedSequence:R-RNO-9613342] Hspa8 [cytosol] [Complex:R-RNO-9626055] Lamp2:Hsp90 [lysosomal membrane]
precedingEvent	[Depolymerisation:R-RNO-9626254] Hspa8:Lamp2 multimers depolymerizes to monomers - Rattus norvegicus
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9626236
summation	[Summation:9626244] Intracellular proteins are targeted for proteolytic degradat...

(precedingEvent)

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