Reactome | Hsp90 dissociates from Lamp2

Schema > Reaction > Entries

authored	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
category	dissociation
compartment	[Compartment:161320] lysosomal lumen [Compartment:17938] lysosomal membrane
created	[InstanceEdit:9626273] Varusai, Thawfeek, 2018-10-26
dbId	9626275
displayName	Hsp90 dissociates from Lamp2
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
followingEvent	[Reaction:R-RNO-9620205] Hspa8:Rnase1 binds Lamp2a - Rattus norvegicus
input	[Complex:R-RNO-9626055] Lamp2:Hsp90 [lysosomal membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9622837] The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hsp90 dissociates from Lamp2
orthologousEvent	[Reaction:R-HSA-9626276] HSP90 dissociates from LAMP2a - Homo sapiens
output	[DefinedSet:R-RNO-9622830] Hsp90aa1, Hsp90ab1 [lysosomal lumen] [EntityWithAccessionedSequence:R-RNO-9620206] Lamp2 [lysosomal membrane]
precedingEvent	[Reaction:R-RNO-9626236] Hspa8 dissociates from Lamp2 - Rattus norvegicus
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9626275
summation	[Summation:9626272] Intracellular proteins are targeted for proteolytic degradat...

(precedingEvent)

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