Reactome | activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane]

Schema > Complex > Entries

compartment	[Compartment:74700] endosome membrane
consumedByEvent	[Reaction:R-RNO-937075] Phosphorylated TAK1 leaves activated TLR receptor complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10146167
displayName	activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane]
hasComponent	[Complex:R-RNO-936965] K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] 2 × [Polymer:R-RNO-450152] K63polyUb [cytosol] 2 × [EntityWithAccessionedSequence:R-RNO-202527] phospho-p-T184,T187-MAP3K7 [cytosol] 2 × [EntityWithAccessionedSequence:R-RNO-167923] Tab1 [cytosol] 2 × [DefinedSet:R-RNO-446874] TAB2,TAB3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-936946] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] - Homo sapiens
maxDepth	7
name	activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex
producedByEvent	[Reaction:R-RNO-936951] Activation of TAK1 complex bound to activated TLR4 complex - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-936946
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-937075] Phosphorylated TAK1 leaves activated TLR receptor complex
(output)	[Reaction:R-RNO-936951] Activation of TAK1 complex bound to activated TLR4 complex
(inferredTo)	[Complex:R-HSA-936946] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane]

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