Reactome | Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[BlackBoxEvent:R-RNO-912527] SHC1 mediates cytokine-induced phosphorylation of GAB2 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10142283
displayName	Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane]
hasMember	[Complex:R-RNO-508246] IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] - Rattus norvegicus [DefinedSet:R-RNO-914052] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] - Rattus norvegicus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-912537] Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] - Homo sapiens
maxDepth	9
name	Interleukin receptor compexes with activated Shc:GRB2:GAB2
producedByEvent	[BlackBoxEvent:R-RNO-453104] Phosphorylated SHC1 recruits GRB2:GAB2 - Rattus norvegicus
schemaClass	DefinedSet
species	[Species:48895] Rattus norvegicus
stId	R-RNO-912537

(input)	[BlackBoxEvent:R-RNO-912527] SHC1 mediates cytokine-induced phosphorylation of GAB2
(output)	[BlackBoxEvent:R-RNO-453104] Phosphorylated SHC1 recruits GRB2:GAB2
(inferredTo)	[DefinedSet:R-HSA-912537] Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane]

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