Reactome | Vdac1 translocates calcium from the cytosol to the mitochondrial intermembrane space

Schema > Reaction > Entries

Vdac1 translocates calcium from the cytosol to the mitochondrial intermembrane space Show undefined attributes

authored	[InstanceEdit:8949721] May, Bruce, 2016-11-28
catalystActivity	[CatalystActivity:8949788] calcium channel activity of Vdac1 [mitochondrial outer membrane]
category	transition
compartment	[Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:8949775] May, Bruce, 2016-11-28
dbId	8949737
displayName	Vdac1 translocates calcium from the cytosol to the mitochondrial intermembrane space
edited	[InstanceEdit:8949721] May, Bruce, 2016-11-28
input	[SimpleEntity:R-ALL-74016] Ca2+ [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8949772] Assay of Ca2+ transport by VDAC1 reconstituted into liposomes [LiteratureReference:8949779] Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function [LiteratureReference:8949764] VDAC closure increases calcium ion flux [LiteratureReference:8949776] Ca2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltage-dependent anion-selective channel (VDAC)
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Vdac1 translocates calcium from the cytosol to the mitochondrial intermembrane space
orthologousEvent	[Reaction:R-HSA-8949145] VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space - Homo sapiens
output	[SimpleEntity:R-ALL-8949232] Ca2+ [mitochondrial intermembrane space]
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8956337] Drago, Ilaria, 2017-01-21
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8949737
summation	[Summation:8953476] Vdac1 is a voltage dependent anion channel that also prefere...

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