Reactome | Pik3r1 [cytosol]

candidateOf	[CandidateSet:R-RNO-1295511] PI3K regulatory subunits [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9693284] RHOF GAPs [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9013126] RHOC GAPs [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9014408] RAC2 GAPs [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9020393] RAC3 GAPs [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9696296] RND1 effectors [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9696290] RND2 effectors [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9696288] RND3 effectors [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9013175] RAC1 GAPs [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9013234] CDC42 GAPs [cytosol] - Rattus norvegicus
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-1806213] PIK3CD:PIK3R1 [cytosol] - Rattus norvegicus [Complex:R-RNO-443399] GPIb-IX-V:vWF:14-3-3-zeta:p85 [plasma membrane] - Rattus norvegicus [Complex:R-RNO-9706282] active FLT3:p-Y GRB10:PI3K [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-443402] GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K - Rattus norvegicus [Reaction:R-RNO-177931] Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10108606
displayName	Pik3r1 [cytosol]
endCoordinate	724
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-74789] PIK3R1 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[CandidateSet:R-RNO-391342] PI3K-regulatory subunits [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-9019558] RHOU effectors [cytosol] - Rattus norvegicus
name	Pik3r1 PIK3R1 Q63787
referenceEntity	[ReferenceGeneProduct:uniprot:Q63787] UniProt:Q63787 Pik3r1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-74789
startCoordinate	1

(hasCandidate)	[CandidateSet:R-RNO-9696290] RND2 effectors [cytosol] [CandidateSet:R-RNO-8981636] RHOA GAPs [cytosol] [CandidateSet:R-RNO-9696288] RND3 effectors [cytosol] [CandidateSet:R-RNO-9013126] RHOC GAPs [cytosol] [CandidateSet:R-RNO-9020366] RHOV effectors [cytosol] [CandidateSet:R-RNO-9013234] CDC42 GAPs [cytosol] [CandidateSet:R-RNO-9014408] RAC2 GAPs [cytosol] [CandidateSet:R-RNO-9013175] RAC1 GAPs [cytosol] [CandidateSet:R-RNO-9693284] RHOF GAPs [cytosol] [CandidateSet:R-RNO-9013040] RHOB GAPs [cytosol] [CandidateSet:R-RNO-9014436] RHOG GAPs [cytosol] [CandidateSet:R-RNO-9017487] RHOJ GAPs [cytosol] [CandidateSet:R-RNO-9020393] RAC3 GAPs [cytosol] [CandidateSet:R-RNO-9696296] RND1 effectors [cytosol] [CandidateSet:R-RNO-1295511] PI3K regulatory subunits [cytosol]
(hasMember)	[CandidateSet:R-RNO-9019558] RHOU effectors [cytosol] [CandidateSet:R-RNO-391342] PI3K-regulatory subunits [cytosol] [DefinedSet:R-RNO-74688] PI3K-regulatory subunit [cytosol]
(hasComponent)	[Complex:R-RNO-9706282] active FLT3:p-Y GRB10:PI3K [plasma membrane] [Complex:R-RNO-9706284] active FLT3:p-Y GRB10:PIK3R1 [plasma membrane] [Complex:R-RNO-443399] GPIb-IX-V:vWF:14-3-3-zeta:p85 [plasma membrane] [Complex:R-RNO-1806213] PIK3CD:PIK3R1 [cytosol] [Complex:R-RNO-1806184] PIK3CB:PIK3R1 [cytosol] [Complex:R-RNO-9607223] Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] [Complex:R-RNO-179864] GRB2:GAB1:PIK3R1 [cytosol] [Complex:R-RNO-1806218] PIK3CA:PIK3R1 [cytosol]
(input)	[Reaction:R-RNO-443402] GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K [Reaction:R-RNO-177931] Binding of PIK3 regulatory alpha subunit to GRB2:GAB1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-74789] PIK3R1 [cytosol]

Pik3r1 [cytosol] Show undefined attributes

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