Reactome | RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate

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RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate Show undefined attributes

catalystActivity	[CatalystActivity:10105432] ribose-5-phosphate isomerase activity of RPIA [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10105434
displayName	RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate
eventOf	[Pathway:R-RNO-71336] Pentose phosphate pathway - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-RNO-73843] 5-Phosphoribose 1-diphosphate biosynthesis - Rattus norvegicus [Reaction:R-RNO-73580] PRPS dimers pyrophosphorylate R5P using ATP - Rattus norvegicus [Reaction:R-RNO-71324] ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-71306] RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate - Homo sapiens
input	[SimpleEntity:R-ALL-29732] RU5P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate D-ribulose 5-phosphate <=> ribose 5-phosphate
output	[SimpleEntity:R-ALL-73578] R5P [cytosol]
precedingEvent	[Reaction:R-RNO-71299] PGD decarboxylates 6-phospho-D-gluconate - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-71306
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-71336] Pentose phosphate pathway
(precedingEvent)	[Pathway:R-RNO-73843] 5-Phosphoribose 1-diphosphate biosynthesis [Reaction:R-RNO-73580] PRPS dimers pyrophosphorylate R5P using ATP [Reaction:R-RNO-71324] ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
(inferredTo)	[Reaction:R-HSA-71306] RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate

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