Reactome | Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10181088] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10165839
displayName	Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane]
hasComponent	[Complex:R-RNO-5654194] Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] [EntityWithAccessionedSequence:R-RNO-74787] Pik3ca [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5654192] Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] - Homo sapiens
maxDepth	9
memberOf	[DefinedSet:R-RNO-2316432] Activator:PI3K [plasma membrane] - Rattus norvegicus
name	Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K
producedByEvent	[Reaction:R-RNO-5654622] Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5654192
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10181088] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane]
(output)	[Reaction:R-RNO-5654622] Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA
(hasMember)	[DefinedSet:R-RNO-2316432] Activator:PI3K [plasma membrane]
(inferredTo)	[Complex:R-HSA-5654192] Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane]

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