Reactome | PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-RNO-5651739] PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10180495
displayName	PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-RNO-54745] FEN1 [nucleoplasm] [GenomeEncodedEntity:R-RNO-5649865] Ghost homologue of SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] [Complex:R-RNO-5651709] PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-53845] POLB [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5651725] PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] - Homo sapiens
maxDepth	4
name	PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA
producedByEvent	[Reaction:R-RNO-5651723] PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5651725
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-5651739] PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB
(output)	[Reaction:R-RNO-5651723] PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate
(inferredTo)	[Complex:R-HSA-5651725] PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm]

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