Reactome | TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2

Schema > Reaction > Entries

TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 Show undefined attributes

category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10180119
displayName	TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2
eventOf	[Pathway:R-RNO-75158] TRAIL signaling - Rattus norvegicus [Pathway:R-RNO-202733] Cell surface interactions at the vascular wall - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5635741] TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 - Homo sapiens
input	[DefinedSet:R-RNO-5634815] TNFRSF10A,TNFRSF10B [plasma membrane] 2 × [EntityWithAccessionedSequence:R-RNO-5633374] TNFRSF10D [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 TNFRSF10D binds TNFRSF10A or TNFRSF10B
output	[DefinedSet:R-RNO-5635735] TNFRSF10A,B:TNFRSF10D [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5635741
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-202733] Cell surface interactions at the vascular wall [Pathway:R-RNO-75158] TRAIL signaling
(inferredTo)	[Reaction:R-HSA-5635741] TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2

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