Reactome | B-WICH complex positively regulates rRNA expression

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B-WICH complex positively regulates rRNA expression Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224633
displayName	B-WICH complex positively regulates rRNA expression
eventOf	[Pathway:R-RNO-5250913] Positive epigenetic regulation of rRNA expression - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24868] transcription initiation-coupled chromatin remodeling
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-RNO-5250947] B-WICH complex binds rDNA promoter - Rattus norvegicus [Reaction:R-RNO-5250930] B-WICH recruits histone acetyltransferases - Rattus norvegicus [Reaction:R-RNO-5250938] B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-5250924] B-WICH complex positively regulates rRNA expression - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	B-WICH complex positively regulates rRNA expression
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5250924
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-5250913] Positive epigenetic regulation of rRNA expression
(inferredTo)	[Pathway:R-HSA-5250924] B-WICH complex positively regulates rRNA expression

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