Reactome | B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9

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B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 Show undefined attributes

catalystActivity	[CatalystActivity:10175848] histone acetyltransferase activity of B-WICH:rDNA Promoter:KAT2B:KAT2A:EP300 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10175850
displayName	B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
eventOf	[Pathway:R-RNO-5250924] B-WICH complex positively regulates rRNA expression - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5250938] B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113560] Ac-CoA [nucleoplasm] [Complex:R-RNO-427402] Nucleosome [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
output	2 × [SimpleEntity:R-ALL-2485002] CoA-SH [nucleoplasm] [Complex:R-RNO-5250919] Nucleosome (H3K9ac) [nucleoplasm]
precedingEvent	[Reaction:R-RNO-5250930] B-WICH recruits histone acetyltransferases - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5250938
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-5250924] B-WICH complex positively regulates rRNA expression
(inferredTo)	[Reaction:R-HSA-5250938] B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9

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