Reactome | phospho-Fos [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-RNO-450327] p-2S-cJUN:p-2S,2T-cFOS [nucleoplasm] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-450292] Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10141579
displayName	phospho-Fos [nucleoplasm]
endCoordinate	380
hasModifiedResidue	[ModifiedResidue:10141574] O-phospho-L-serine at 362 (in Homo sapiens) [ModifiedResidue:10141575] O-phospho-L-serine at 374 (in Homo sapiens) [ModifiedResidue:10141576] O-phospho-L-threonine at 325 (in Homo sapiens) [ModifiedResidue:10141577] O-phospho-L-threonine at 331 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-450283] p-T325,T331,S362,S374-FOS [nucleoplasm] - Homo sapiens
maxDepth	1
name	phospho-Fos p-T325,T331,S362,S374-FOS P12841
producedByEvent	[Reaction:R-RNO-450325] c-FOS activation by phospho ERK1/2 - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:P12841] UniProt:P12841 Fos
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-450283
startCoordinate	1

(input)	[Reaction:R-RNO-450292] Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.
(output)	[Reaction:R-RNO-450325] c-FOS activation by phospho ERK1/2
(hasComponent)	[Complex:R-RNO-450327] p-2S-cJUN:p-2S,2T-cFOS [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-450283] p-T325,T331,S362,S374-FOS [nucleoplasm]

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