Reactome | Post-transcriptional silencing by small RNAs

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Post-transcriptional silencing by small RNAs Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223779
displayName	Post-transcriptional silencing by small RNAs
eventOf	[Pathway:R-RNO-211000] Gene Silencing by RNA - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:160929] regulatory ncRNA-mediated post-transcriptional gene silencing
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-426520] Endonucleolytic RISC hydrolyzes target RNAs - Rattus norvegicus [Reaction:R-RNO-426489] RISC binds inexactly matching target RNAs - Rattus norvegicus [Reaction:R-RNO-426522] Nonendonucleolytic RISC binds exactly matching target RNAs - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-426496] Post-transcriptional silencing by small RNAs - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Post-transcriptional silencing by small RNAs
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-426496
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-211000] Gene Silencing by RNA
(inferredTo)	[Pathway:R-HSA-426496] Post-transcriptional silencing by small RNAs

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