Reactome | Gene Silencing by RNA

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Gene Silencing by RNA Show undefined attributes

compartment	[Compartment:7660] nucleoplasm [Compartment:13231] nuclear envelope [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223415
displayName	Gene Silencing by RNA
eventOf	[TopLevelPathway:R-RNO-74160] Gene expression (Transcription) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:160777] regulatory ncRNA-mediated gene silencing
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-203927] MicroRNA (miRNA) biogenesis - Rattus norvegicus [Pathway:R-RNO-426486] Small interfering RNA (siRNA) biogenesis - Rattus norvegicus [Pathway:R-RNO-426496] Post-transcriptional silencing by small RNAs - Rattus norvegicus [Pathway:R-RNO-5578749] Transcriptional regulation by small RNAs - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-211000] Gene Silencing by RNA - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Gene Silencing by RNA
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-211000
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-RNO-74160] Gene expression (Transcription)
(hasEncapsulatedEvent)	[Pathway:R-RNO-9764265] Regulation of CDH1 Expression and Function
(inferredTo)	[Pathway:R-HSA-211000] Gene Silencing by RNA