Reactome | p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-3928519] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-3928595] N-WASP binds ARP2/3 and G-actin - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10172218
displayName	p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane]
hasComponent	[Complex:R-RNO-3928566] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] [SimpleEntity:R-ALL-179856] PI(4,5)P2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-3928536] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] - Homo sapiens
maxDepth	7
name	p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2
producedByEvent	[Reaction:R-RNO-3928601] CDC42 and PIP2 bind WASL, activating it - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3928536
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-3928595] N-WASP binds ARP2/3 and G-actin
(hasComponent)	[Complex:R-RNO-3928519] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane]
(output)	[Reaction:R-RNO-3928601] CDC42 and PIP2 bind WASL, activating it
(inferredTo)	[Complex:R-HSA-3928536] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane]

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