Reactome | L1 binds to AP-2 Clathrin complex

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L1 binds to AP-2 Clathrin complex Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10135731
displayName	L1 binds to AP-2 Clathrin complex
eventOf	[Pathway:R-RNO-437239] Recycling pathway of L1 - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-555065] Formation of clathrin coated vesicle - Rattus norvegicus [Reaction:R-RNO-392749] Transport of L1 into endosomes - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-392748] L1 binds to AP-2 Clathrin complex - Homo sapiens
input	[Complex:R-RNO-177505] Clathrin:AP-2 complex [plasma membrane] [EntityWithAccessionedSequence:R-RNO-191465] L1cam [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	L1 binds to AP-2 Clathrin complex
output	[Complex:R-RNO-555064] L1:clathrin-coated vesicle [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-392748
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-437239] Recycling pathway of L1
(precedingEvent)	[Reaction:R-RNO-555065] Formation of clathrin coated vesicle [Reaction:R-RNO-392749] Transport of L1 into endosomes
(inferredTo)	[Reaction:R-HSA-392748] L1 binds to AP-2 Clathrin complex

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