Reactome | Clathrin:AP-2 complex [plasma membrane]

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Clathrin:AP-2 complex [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-2130309] Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] - Rattus norvegicus [Complex:R-RNO-555064] L1:clathrin-coated vesicle [plasma membrane] - Rattus norvegicus [Complex:R-RNO-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-2130640] Recruitment of clathrin coated vesicle by Ii - Rattus norvegicus [Reaction:R-RNO-392748] L1 binds to AP-2 Clathrin complex - Rattus norvegicus [Reaction:R-RNO-6784735] PCSK9:LDLR bind to Clathrin - Rattus norvegicus [Reaction:R-RNO-8855131] VLDLR:PCSK9 binds Clathrin-coated vesicles - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10120149
displayName	Clathrin:AP-2 complex [plasma membrane]
hasComponent	[Complex:R-RNO-177480] AP-2 complex [plasma membrane] [Complex:R-RNO-177482] Clathrin [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-177505] Clathrin:AP-2 complex [plasma membrane] - Homo sapiens
maxDepth	4
name	Clathrin:AP-2 complex
producedByEvent	[Reaction:R-RNO-445071] Reinsertion of L1 into the plasma membrane - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-177505
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-RNO-2130640] Recruitment of clathrin coated vesicle by Ii [Reaction:R-RNO-392748] L1 binds to AP-2 Clathrin complex [Reaction:R-RNO-6784735] PCSK9:LDLR bind to Clathrin [Reaction:R-RNO-8855131] VLDLR:PCSK9 binds Clathrin-coated vesicles
(hasComponent)	[Complex:R-RNO-2130309] Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] [Complex:R-RNO-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] [Complex:R-RNO-445005] pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome] [Complex:R-RNO-555064] L1:clathrin-coated vesicle [plasma membrane] [Complex:R-RNO-392743] L1:AP-2 Clathrin complex [clathrin-coated endocytic vesicle] [Complex:R-RNO-6784733] PCSK9:LDLR:Clathrin:AP2 [plasma membrane] [Complex:R-RNO-8855134] VLDL:PCSK9:Clathrin:AP2 [plasma membrane] [Complex:R-RNO-177490] Activated TrkA receptor complex:Clathrin-coated vesicle:Endophilin [plasma membrane]
(output)	[Reaction:R-RNO-445071] Reinsertion of L1 into the plasma membrane
(inferredTo)	[Complex:R-HSA-177505] Clathrin:AP-2 complex [plasma membrane]

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