Reactome | SHP-1 and SHP-2 bind pBTLA

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10134947
displayName	SHP-1 and SHP-2 bind pBTLA
eventOf	[Pathway:R-RNO-9927353] Co-inhibition by BTLA - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-389941] SHP-1 and SHP-2 bind pBTLA - Homo sapiens
input	[Complex:R-RNO-389920] p-BTLA-HVEM complex [plasma membrane] [DefinedSet:R-RNO-389744] PTPN6,PTPN11 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SHP-1 and SHP-2 bind pBTLA
output	[Complex:R-RNO-389935] SHP-1/SHP-2:pBTLA:HVEM [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-389941
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-9927353] Co-inhibition by BTLA
(inferredTo)	[Reaction:R-HSA-389941] SHP-1 and SHP-2 bind pBTLA

Cite Us!