Reactome | Beta-catenin independent WNT signaling

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224481
displayName	Beta-catenin independent WNT signaling
eventOf	[Pathway:R-RNO-195721] Signaling by WNT - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:937917] non-canonical Wnt signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-4086400] PCP/CE pathway - Rattus norvegicus [Pathway:R-RNO-4086398] Ca2+ pathway - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-3858494] Beta-catenin independent WNT signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Beta-catenin independent WNT signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3858494
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-195721] Signaling by WNT
(hasEncapsulatedEvent)	[Pathway:R-RNO-5663220] RHO GTPases Activate Formins [Pathway:R-RNO-3238698] WNT ligand biogenesis and trafficking
(inferredTo)	[Pathway:R-HSA-3858494] Beta-catenin independent WNT signaling

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