Reactome | p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10167932] guanyl-nucleotide exchange factor activity of p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-RNO-2730840] Activation of RAC1 by VAV - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10167929
displayName	p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]
hasComponent	[Complex:R-RNO-2424460] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] [DefinedSet:R-RNO-2029115] p-VAV family [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Homo sapiens
maxDepth	6
name	p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV
producedByEvent	[Reaction:R-RNO-2730841] Phosphorylation and activation of VAV - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2685666
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-2730840] Activation of RAC1 by VAV
(physicalEntity)	[CatalystActivity:10167932] guanyl-nucleotide exchange factor activity of p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]
(output)	[Reaction:R-RNO-2730841] Phosphorylation and activation of VAV
(inferredTo)	[Complex:R-HSA-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]

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