Reactome | p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]

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p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:2730857] guanyl-nucleotide exchange factor activity of p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-2730840] Activation of RAC1 by VAV - Homo sapiens
created	[InstanceEdit:2685710] Garapati, P V, 2012-12-03
dbId	2685666
displayName	p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]
hasComponent	[Complex:R-HSA-2424460] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] [DefinedSet:R-HSA-2029115] p-VAV family [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Mus musculus [Complex:R-RNO-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Rattus norvegicus [Complex:R-CFA-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Canis familiaris [Complex:R-BTA-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Bos taurus [Complex:R-SSC-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Sus scrofa [Complex:R-XTR-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Gallus gallus [Complex:R-DME-2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - Drosophila melanogaster
isChimeric	false
maxDepth	6
modified	[InstanceEdit:8951566] Jupe, Steve, 2016-12-08
name	p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV
producedByEvent	[Reaction:R-HSA-2730841] Phosphorylation and activation of VAV - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2685666
updateTrackers	[UpdateTracker:9889566] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v49:[updateContainedComponent] [UpdateTracker:9889160] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v48:[updateContainedComponent] [UpdateTracker:9898318] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v63:[updateContainedComponent] [UpdateTracker:9896170] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v60:[removeHasComponent] [UpdateTracker:9892397] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v53:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9889566] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v49:[updateContainedComponent] [UpdateTracker:9889160] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v48:[updateContainedComponent] [UpdateTracker:9898318] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v63:[updateContainedComponent] [UpdateTracker:9896170] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v60:[removeHasComponent] [UpdateTracker:9892397] Update Tracker - [Complex:2685666] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] - v53:[updateContainedComponent]
(output)	[Reaction:R-HSA-2730841] Phosphorylation and activation of VAV
(input)	[Reaction:R-HSA-2730840] Activation of RAC1 by VAV
(physicalEntity)	[CatalystActivity:2730857] guanyl-nucleotide exchange factor activity of p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane]

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