Reactome | DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10166534] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10166533
displayName	DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane]
hasComponent	[Complex:R-RNO-2395423] DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] [EntityWithAccessionedSequence:R-RNO-1861712] phospho-p-6Y-SYK [cytosol] [Complex:R-RNO-74693] PI3K [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2424456] DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] - Homo sapiens
maxDepth	7
name	DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K
producedByEvent	[Reaction:R-RNO-2424482] p85 regulatory unit of PI3K binds p-6Y-SYK - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2424456
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10166534] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane]
(output)	[Reaction:R-RNO-2424482] p85 regulatory unit of PI3K binds p-6Y-SYK
(inferredTo)	[Complex:R-HSA-2424456] DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane]

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