Reactome | phospho-p-6Y-SYK [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-5621160] pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10150428
displayName	phospho-p-6Y-SYK [cytosol]
endCoordinate	635
hasModifiedResidue	[ModifiedResidue:10138821] O4'-phospho-L-tyrosine at 348 (in Homo sapiens) [ModifiedResidue:10150422] O4'-phospho-L-tyrosine at 352 (in Homo sapiens) [ModifiedResidue:10150423] O4'-phospho-L-tyrosine at 525 (in Homo sapiens) [ModifiedResidue:10150424] O4'-phospho-L-tyrosine at 526 (in Homo sapiens) [ModifiedResidue:10150425] O4'-phospho-L-tyrosine at 131 (in Homo sapiens) [ModifiedResidue:10150426] O4'-phospho-L-tyrosine at 323 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-1861712] p-6Y-SYK [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-RNO-2424474] p-SYK,p-BTK [cytosol] - Rattus norvegicus [DefinedSet:R-RNO-2396556] SYK/LCK/ZAP-70 [cytosol] - Rattus norvegicus
name	phospho-p-6Y-SYK Q64725
referenceEntity	[ReferenceGeneProduct:uniprot:Q64725] UniProt:Q64725 Syk
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1861712
startCoordinate	1

(activeUnit)	[CatalystActivity:10178992] protein tyrosine kinase activity of pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYK [plasma membrane] [CatalystActivity:10178985] protein tyrosine kinase activity of pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2 [plasma membrane] [CatalystActivity:10162523] protein tyrosine kinase activity of clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] [CatalystActivity:10167899] protein tyrosine kinase activity of Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] [CatalystActivity:10150457] protein tyrosine kinase activity of Antigen:p-BCR:p-SYK [plasma membrane] [CatalystActivity:10162496] protein tyrosine kinase activity of clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane]
(hasComponent)	[Complex:R-RNO-5621160] pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] [Complex:R-RNO-2424456] DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] [Complex:R-RNO-2395411] DAP12 Receptors:p-DAP12:p-6Y-SYK [plasma membrane] [Complex:R-RNO-2454231] Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] [Complex:R-RNO-983690] Antigen:p-BCR:p-SYK [plasma membrane] [Complex:R-RNO-2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
(hasMember)	[DefinedSet:R-RNO-2424474] p-SYK,p-BTK [cytosol] [DefinedSet:R-RNO-2396556] SYK/LCK/ZAP-70 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-1861712] p-6Y-SYK [cytosol]

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